Skin Rejuvenation

How Rejuran Helps with Pigmentation and Uneven Skin Tone

Rejuran for Hyperpigmentation: What You Need to Know

Struggling with dark spots or patchy skin tone? You’re not alone—and there’s a powerful topical treatment that’s getting a lot of buzz: Rejuran®. Known for its skin-healing powers, it’s quickly becoming a go-to for anyone wanting brighter, more even skin.

So, What Exactly Is Rejuran?

Rejuran is a cutting-edge treatment made from salmon DNA (yes, really!). Why salmon? Because their DNA is nearly identical to ours—about 97% compatible. That means your skin can easily absorb and benefit from it.

Using something called DOT™ (DNA Optimizing Technology), Rejuran delivers special ingredients deep into your skin. The main stars are polynucleotides (PN) and c-PDRN, which work to repair, heal, and refresh your skin from within. At LaserAway, we apply Rejuran treatments as topical boosters after a Clear + Brilliant or RF microneedling treatment to enhance your results. 

How Rejuran Works Its Magic

Rejuran isn’t just another skincare trend—it actually helps your skin heal itself. It boosts cell turnover and collagen production (a key to plump, youthful skin). Those powerful polynucleotides also fix damaged DNA and reduce signs of aging, sun damage, and uneven tone.

Bonus: It has anti-inflammatory properties, so it helps calm redness and irritation. You’ll notice your skin looking clearer, brighter, and more balanced. It really amps up your skin’s glow, giving you that ‘glass skin’ look!

Meet the Rejuran Tone-Up Booster for Pigmentation

If you’re specifically dealing with dark spots, melasma, or dull skin, Rejuran has a solution: the Tone-Up Booster.

What’s inside:

  • Low molecular weight hydrolyzed DNA
  • Hyaluronic acid (for hydration)
  • Tranexamic acid and glutathione (great for fading spots)
  • Vitamin C (a glow-boosting powerhouse)

What it does:

  • Fades hyperpigmentation and melasma
  • Brightens dull skin
  • Deeply hydrates and revives your natural glow

As Arsema Hawariat, RN at LaserAway explains, “The Tone-Up Booster is great if your main concern is dull or dark spots, as it helps fade hyperpigmentation and brightens your complexion thanks to ingredients like vitamin C and glutathione.”

The Best Way to Even Your Skin Tone

Want serious results? We pair Rejuran Tone-Up Booster with our top energy-based treatments: Clear + Brilliant® and Potenza™ RF Microneedling.

Here’s why this combo works so well:

  • Clear + Brilliant or Potenza create tiny channels in the skin, encouraging it to renew itself while prepping it to soak in treatment ingredients.
  • The Rejuran Booster fills those microchannels with brightening, hydrating ingredients—supercharging your glow.

Arsema Hawariat, RN at LaserAway says it best: “It’s essentially like you’re getting two powerhouse treatments in one!”

When Will You See Results?

You’ll usually start to notice brighter, smoother skin in about 4 to 6 weeks. For the best results, plan for a series of 3 to 6 sessions.

  • If you’re combining it with Clear + Brilliant®, treatments are spaced about 2 to 4 weeks apart.
  • With Potenza RF Microneedling, you’ll go every 4 to 6 weeks.

Your collagen keeps building between sessions, so your skin just keeps getting better over time.

Why Get Rejuran at LaserAway?

LaserAway offers a specially formulated Rejuran Tone-Up Booster that’s designed to tackle pigmentation concerns head-on. When paired with Clear + Brilliant or Potenza RF microneedling, it’s a total game-changer for uneven tone and dark spots. You’ll walk away with smoother, more even skin, fewer dark spots and less pigmentation, and a healthy, radiant glow. 

Want to learn more about Rejuran? Reach out to one of our treatment specialists for a complimentary consultation. 

References

  1. “Polynucleotide-Based Treatments For Various Facial Scars Including Combat Injuries,” Journal of Dermatological Treatment, December 2024.
  2. “Radiofrequency Microneedling: A Comprehensive and Critical Review,” Dermatologic Surgery, June 2021
  3. “The 1440 nm and 1927 nm Nonablative Fractional Diode Laser: Current Trends and Future Directions,” Journal of Drugs in Dermatology, August 2020.